We are proud that we were able to support this review on the prevalence, incidence and profile of musculoskeletal injuries in para-athletes. Sports for athletes with a disability is gaining in popularity and is growing rapidly in terms of competitiveness. Research on the protection of the health of these athletes is, however, lagging behind. With this systematic review, we provide an overview of what is known on the injuries sustained by para-athletes. At the same time, we provide future direction by calling out gaps in the evidence.